Fig. 7
From: The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer
Tlr7 is common in the stroma but not in the epithelium of human pancreatic neoplasms. Left: Transcript count per million (TPM) from RNA-seq in epithelial and stromal laser capture microdissected samples from PanIN, IPMN, and PDAC samples for Tlr7 (a), Tlr8 (c), and Unc93b1 (e). Data displayed as interquartile range, with whiskers depicting 2.5th–97.5th perecentile. Right: Proportions of samples positive and negative for Tlr7 (b), Tlr8 (d), and Unc93b1 (f) based on the threshold of 1 TPM. Sample size for each category of neoplasm (PanIN, IPMN, and PDAC) and tumor compartment (epithelium and stroma) are shown in the center of the plot, with the outer values depicting absolute frequency of positive and negative expression
