Fig. 1
Crystal structure of Vrg4 bound to GMP. a Crystal structure of Vrg4 with helices coloured blue (N-terminus) to red (C-terminus). The binding cavity is open to the Golgi lumen, and shown as a transparent surface (wheat). The three different positions observed for the GMP molecule are overlaid in blue, orange and pink. The position of the lipid bilayer is indicated by white dashed lines. b An overlay showing the three GMP molecules as presented in a, with arrows highlighting the changes in positions observed for the nucleoside and phosphate groups. c, d, e Zoomed in views of the binding site from chains C, D and E respectively, showing the different positions and interactions made to GMP in the crystal structure
