Fig. 3 | Nature Communications

Fig. 3

From: Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer

Fig. 3

The FYNN motif mediates nucleotide discrimination. a Representative IC50 curves determined for GMP in wild type (WT), N220A and N221A variants. b Representative IC50 curves determined for AMP in wild type (WT), N220A and N221A variants. The chemical structures of GMP and AMP are shown for reference. Insets show the calculated IC50 value from three independent experiments, errors shown are s.d. of the mean. Source data are provided as a Source Data file

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