Fig. 5
From: Genetic mapping and evolutionary analysis of human-expanded cognitive networks
Cortical disorder involvement and HAR-BRAIN gene expression. Left panel shows brain maps of cortical involvement across five major psychiatric disorders (e.g., schizophrenia, bipolar disorder, autism spectrum disorder, major depression, and obsessive-compulsive disorder). Middle panel shows correlation between HAR-BRAIN gene expression and disorder involvement (Pearson’s r = 0.437, p < 0.001; corrected for cortical volume), and right panel shows the comparison of the correlation coefficient to null distributions generated by random BRAIN (NULL1; p = 0.022) and ECE genes (NULL2; p < 0.001, permutation test, 10,000 permutations). Source data provided as Source Data file
