Fig. 1
From: Regulation of the ER stress response by a mitochondrial microprotein
PIGBOS is a conserved microprotein. a Detection of a unique PIGBOS tryptic peptide by proteomics (MS/MS spectrum as shown) and the entire 54 amino acid human PIGBOS microprotein with detected tryptic peptide (red). b PIGBOS1 gene contains two exons and is located on the opposite strand of the PIGB gene on chromosome 15. The PIGBOS protein coding sequence (CDS) in exon 2 is highlighted in green. c Western blot of rat tissues detects endogenous PIGBOS microprotein expression. d A logo plot generated from the sequence alignment of PIGBOS microprotein from multiple species reveals conserved amino acids including the transmembrane region between amino acids 7–29 (red) flanked by a N-terminal region (N-Term, aa 1–6) and a C-terminal region (C-Term, aa 30–54)
