Fig. 3
Pu-erh tea reduced the abundance of BSH microbes and BSH activity. a Abundance of BSH enriched microbes in ileum of mice undergoing Pu-erh tea consumption. n = 5 individuals/group. b Abundance of BSH enriched microbes in feces of humans consuming Pu-erh tea. n = 13 individuals/group. c The microbial BSH enzyme activity in the ileal contents of mice treated with Pu-erh tea. d The microbial BSH activity in human feces from subjects on Pu-erh tea consumption. The functional profiles were identified by metagenomic analysis utilizing both KEGG and eggNOG databases. BSH related proteins ranked in the top ten are shown and the mean abundances are illustrated as the horizontal line in each group. e Ileal BSH activity in mice on Pu-erh tea consumption. n = 8 individuals/group. f Fecal BSH activity inhuman subjects on Pu-erh tea consumption. n = 13 individuals/group. Data were expressed as mean ± SEM. Differences in the data for mice and human subjects were assessed by the Mann–Whitney U test and Wilcoxon rank-sum test, respectively, *p < 0.05, #p < 0.005
