Fig. 3
From: Increased yields and biological potency of knob-into-hole-based soluble MHC class II molecules
Key junctional, linker and motif sequences for hKIH-based mouse pMHCII and empty hKIH-based human pMHCII. a Key amino acid sequences of a mouse pMHCII molecule encoding BDC2.5mi/IAαd/IAβg7 heterodimerized using a carboxyterminal human IgG1-Fc-based KIH. b Key amino acid sequences for “empty” human MHCII molecules encoding DRA*0101 MHCα and DRB1, DRB3, DRB4 or DRB5 MHCβ chains heterodimerized using a carboxyterminal human IgG1-Fc-based KIH
