Fig. 6: Ift88 is involved in maintaining epithelial-like polarity.
From: Glucose homeostasis is regulated by pancreatic β-cell cilia via endosomal EphA-processing
a F- and G-actin quantification in in shIft88 1 and 2 and scrambled RNA (control), mean ± s.d. b Modification—actin visualized by phalloidin staining (red) in shIft88 cells and scrambled RNA (control) (scale bar 10 µm). c Biotinylated EphrinA5-Fc uptake in shIft88 cells treated with cytochalasin-D (2 µM, 3 h) and vehicle, mean ± s.d. d β-Catenin, Snail1, Slug, Vimentin, E-Cadherin protein levels (n = 3) in shIft88 1 and 2 cells and controls and quantification, mean ± s.d. e GTP-bound Rac1 levels in shIft88 1 and 2 and control cells treated with EphrinA5-Fc or vehicle.
