Table 1 Comparison of yeast cell factories for production of aromatic chemicals

From: Rewiring carbon metabolism in yeast for high level production of aromatic chemicals

Target compound

Characteristics of study

Titer (g L−1)

Yield (mg g–1 glucose)

Productivity (mg L–1 h–1)

Origin

Shikimic acid

Shake flask

1.979

54.4

NDa

22

Phenylethanol

Shake flask

0.408

20.4

NDa

57

Resveratrol

Fed-batch bioreactor

0.812

9.2

7.4

58

Naringenin

Batch bioreactor

0.113

5.6

3.0

31

Vanillin ß-d-glucoside

Batch bioreactor

0.306

15.3

NDa

59

Breviscapine

Fed-batch bioreactor

0.293

NDa

NDa

60

Para-coumaric acid

Fed-batch deep-well plate

1.93

NDa

NDa

30

Para-coumaric acid

Shake flask using FeadBeadsb

3.02 (3.1)c

151.1 (154.9)c

31.5 (32.3)c

This study

Para-coumaric acid

Fed-batch bioreactor

10.4 (12.5)c

125.3 (139.6)c

107.9 (130.1)c

This study

  1. aND, not determined
  2. bSlow release of glucose from elastomer discs
  3. cValues for diploid strains