Fig. 3 | Nature Communications

Fig. 3

From: Inhibitory microcircuits for top-down plasticity of sensory representations

Fig. 3

Inhibitory structure guides excitatory plasticity in the absence of reward. a Illustration of changes in the excitatory structure. b Evolution of excitatory connections. Mean and s.d. of the connections from the vertically tuned PCs to PCs tuned to other orientations (purple), from PCs tuned to other orientations to the vertically tuned PC population (green), and from others to others (yellow). c Final excitatory weight matrix. Neurons 1–100 are tuned to the vertical bar, 100–200 to an angled bar, etc. d Tuning of excitatory populations before the rewarded phase (black) and at the end of the refinement phase (red) (number of spikes during 50 ms after stimulus onset averaged over all occurrences of that stimulus in 1 s of simulation). e Illustration of the inhibitory structure after the rewarded phase. f Evolution of the SST-to-PVs connections (mean and s.d.), grouped according to SST tuning (colours match the colours of the connections in e). g SST-to-PV connections after the refinement phase, grouped by SST tuning (error bars: s.d.). h Tuning of PVs after the refinement phase

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