Fig. 2

Linear regression model of ROI contributions to MEG data. a Temporal variations of the linear mixing model coefficients shown in each region of interest, following electrocutaneous stimulation of the index finger (0 ms). The data from left and right index finger stimulation were pooled for greater statistical power. The linear coefficient time series are shown for contralateral posterior thalamus (top, with early peak marked with an arrow), primary somatosensory (S1, middle), and visual (V1, bottom) ROIs in CB and SC subjects. Shading indicates standard error of the mean estimates. Gray-shaded boxes highlight segments of significant differences between the two groups (p ≤ 0.05), with their borders colored according to the group showing stronger V1 contribution (two-tailed independent t test, p ≤ 0.05—not corrected for multiple comparison due to a limited number of participants). The thalamus model coefficients are shown only over the first 50 ms after stimulus onset to emphasize the early peak around 20 ms (black arrow). b Average model coefficients in V1 within the [35, 50]-ms time window showed greater V1 contribution in CB vs. SC. Mixed model ANOVA with hemisphere as within-subject variable and group as between-subject variable: no main effect of hemisphere or interactions between hemisphere and group, but significant effect of group (F(1) = 15.6, p = 0.001) reflecting stronger activity in V1 for CB subjects