Fig. 5: Association of regulatory genetic variants in cis and trans with plasma proteins.
From: Profiling of the plasma proteome across different stages of human heart failure
Regional association plots of genetic loci in a cis-associated with thrombospondin-2, and b in trans-associated with C5a at the CFH locus. Plots depict all single nucleotide polymorphisms (SNPs) within ±500 kb of the lead SNP. Circles indicate SNPs with genomic position on the x axis (human genome build 19), p value on the left-hand y axis and recombination rate on the right-hand y axis. Colors indicate pairwise linkage disequilibrium of each SNP with the lead SNP at each locus.
