Fig. 2
From: Assembly of chromosome-scale contigs by efficiently resolving repetitive sequences with long reads
An illustration of identifying tandemly repetitive sequences by HERA. a A tandemly repetitive sequence on chromosome 5 of R498 with a unit length of 65 kb. The upper green horizontal bar represents the assembled sequence lacking a unit and the lower blue bar represents the BioNano map. b A repetitive sequence on chromosome 8 of R498 with a unit length of 22 kb. c The length distribution of HERA generated tiling paths for the repeat shown in (a). The paths are divided into several clusters and the distances between adjacent peaks are 65 kb which matched the repeat unit length in (a). The second peak represents the whole region of two repeat units (130 kb). d The length distribution of HERA generated tiling paths for the repeat in (b). The paths are divided into two clusters and the distance between the two peaks is around 35 kb. e The schematic representation of the repeat region in (b). In this region, there are two highly similar repeat units of 22 kb (rectangle) being separated by one of the two dissimilar repeat units of 13 kb (triangle). Ref, the full repeat region; ctg, the flanking sequences to be connected; cns1 and cns2, excluding the flanking sequences shown in ctg, correspond to the second and the first peak in (d), respectively.
