Fig. 5 | Nature Communications

Fig. 5

From: RNA secondary structure prediction using an ensemble of two-dimensional deep neural networks and transfer learning

Fig. 5

Comparison of SPOT-RNA prediction with the native structure of a Pistol Ribozyme, Mango aptamer, and Adenovirus Virus-associated RNA. The secondary structure of a Pistol Ribozyme (chain A and B in PDB ID 6r47), the Mango Aptamer (chain B in PDB ID 6e8u), and the adenovirus virus-associated RNA (chain C in PDB ID 6ol3) represented by arc diagrams with canonical base pair (BP) in blue color, noncanonical, pseduoknot BP and lone pair in green color, and wrongly predicted BP in magenta color: a predicted structure by SPOT-RNA (on left), with 93\(\%\) precision and 41\(\%\) sensitivity, as compared with the native structure (on right) for the Pistol Ribozyme, b the predicted structure by SPOT-RNA (on left) with 100\(\%\) precision and 26\(\%\) sensitivity, as compared with the native structure (on right) for the Mango aptamer, c the predicted structure by SPOT-RNA (on left) with 66\(\%\) precision and 60\(\%\) sensitivity, as compared with the native structure (on right) for the adenovirus virus-associated RNA.

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