Fig. 3
From: Monkeys mutant for PKD1 recapitulate human autosomal dominant polycystic kidney disease
Mimicking the result of several “two-hit” mutations. a H&E-stained images and the expressions of PC1 in mild-type kidneys. The upper row of H&E-stained images shows cyst formation in the kidneys. The lower row of immunohistochemically stained images shows the expression of PC1. “G” indicates glomeruli, “Cy” indicates cysts, and “CT” indicates collecting ducts. Arrowheads indicate PC1-negative tubules. Scale bar, 100 µm. b The expressions of AQP1, AQP2, and PC1 in a mild-type kidney. Asterisks indicate cysts. Scale bar, 100 µm.
