Fig. 7

Ability of HiC-Reg to capture significant interactions and TADs in new cell lines. a Enrichment of CTCF motifs in four configurations for cross-cell predictions. Shown are the fold enrichments when testing using a model trained on a different cell line or an ensemble of models using MULTI-CELL features. The diagonal entries correspond to the fold enrichment obtained in the cross-validation setting. b Fold enrichment of ChIA-PET interactions in predicted interactions when training on a different cell line, as well as when using the MULTI-CELL ensemble. c Jaccard coefficient-based similarity of TADs called on true and predicted interaction counts when training on a different cell line. Shown are Jaccard similarity values for three chromosomes, 14, 17, and 19. Source data are provided as a Source Data file.