Fig. 2
From: Primary decidual zone formation requires Scribble for pregnancy success in mice
Implantation is aberrant in Scribf/fPgrcre/+ mice. a Histology of day 5 of implantation sites in each genotype. Scale bar, 200 μm. Arrowheads indicate the location of embryos. b 3D imaging of day 5 implantation sites in Scribf/f, Scribf/fLtfcre/+, and Scribf/fPgrcre/+ females. Images of E-cadherin immunostaining, segmented, and 3D rendered images of day 5 implantation sites in each genotype show the aberrant crypt-gland structure in Scribf/fPgrcre/+ females. Images were generated by a Nikon A1R Multiphoton Microscope with LWD 16× objective with 3 µm Z-stack. Scale bar, 200 μm. Asterisks indicate the location of blastocysts. Each image is a representative of at least three independent experiments. M mesometrial pole, AM antimesometrial pole, le luminal epithelium, ge glandular epithelium, st stroma.
