Fig. 1: Loss of TNFR2 expression does not reduce LM in male mice. | Nature Communications

Fig. 1: Loss of TNFR2 expression does not reduce LM in male mice.

From: Sexual dimorphism and the role of estrogen in the immune microenvironment of liver metastases

Fig. 1

Male Bl6 mice were inoculated with 5 × 104 MC-38 cells via the intrasplenic/portal route. Liver metastases were enumerated 20 days later. Shown in a are pooled data of two experiments and in b representative livers from tumor-injected mice (n = 8 for WT, n = 6 for TNFR1−/−, and n=6 for TNFR2−/− mice; horizontal bars denote median values). NS, not significant as determined by the Mann–Whitney test. Box and whiskers graphs: the box extends from the 25th to 75th percentiles, the middle line denotes the median and the whiskers extends from the minimum to the maximum value.

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