Table 3 Maximal genetic similarity metrics are highly predictive of case child temporal distance from origin household.

From: High-resolution micro-epidemiology of parasite spatial and temporal dynamics in a high malaria transmission setting in Kenya

  

BSS %a

BSS p-valueb

PSS %a

PSS p-valueb

L1 %a

L1 p-valueb

Household of origin

 

18.4

0.06

15.7

0.11

10.5

0.20

Temporal distance from origin household (% maximal temporal distance)

±10 days (5%)

42.1

<0.01

42.1

<0.01

34.2

<0.01

±30 days (15%)

50.0

0.03

50.0

0.03

55.3

<0.01

±60 days (30%)

60.5

0.02

60.5

0.02

65.8

<0.01

Geographic distance from origin household (% maximal geographic distance)

within 0.75 km (5%)

18.4

0.15

21.1

0.09

13.2

0.43

within 2.25 km (15%)

26.3

0.40

26.3

0.40

23.7

0.57

within 4.5 km (30%)

36.8

0.81

36.8

0.81

39.4

0.63

  1. aPercentage of case children (n = 38) for which maximal binary share score, proportional share score, and L1 norm correctly predict case child household of origin OR temporal distance from origin household (within three temporal windows: ±10, 30, or 60 days representing 5, 15, or 30% of the maximum time between cases) OR geographic distance from origin household (within three ranges – 5, 15, and 30% maximal geographic distance)
  2. bFisher’s Exact Test p-value based on assumption that cases are evenly distributed throughout time and across geographic space
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