Table 1 Mutations observed in evolved lines compared to their ancestors.
From: Molecular signatures of aneuploidy-driven adaptive evolution
Substitution/Strain | WT | D1 | D2 | D5 | D8 | D9 | D10 | D11 | D12 | D13 | D14 | D15 | D16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Chromosome length (kb) | 230 | 813 | 576 | 562 | 439 | 745 | 666 | 1080 | 924 | 780 | 1090 | 948 | |
Total number of mutations (substitutions and indels) | 5 | 23 | 32 | 26 | 37 | 18 | 48 | 42 | 30 | 30 | 24 | 33 | 30 |
Mutations on duplicated chr. | 7 | 8 | 5 | 9 | 5 | 14 | 7 | 11 | 9 | 7 | 12 | 11 | |
Total substitutions (cod/ncod) | 3/1 | 5/11 | 3/11 | 15/6 | 15/15 | 8/5 | 19/10 | 13/10 | 13/8 | 9/7 | 8/14 | 13/13 | 13/9 |
Missense | 2 | 3 | 2 | 10 | 10 | 6 | 11 | 8 | 9 | 6 | 6 | 10 | 8 |
Nonsense | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 2 |
Silent | 1 | 1 | 1 | 5 | 4 | 1 | 7 | 5 | 4 | 3 | 2 | 2 | 3 |
Total indels (cod/ncod) | 1/0 | 2/5 | 3/15 | 0/5 | 1/6 | 0/5 | 13/6 | 5/14 | 2/7 | 2/12 | 0/2 | 1/6 | 2/6 |
