Fig. 6: Discrimination of three types of biothiols by Au(III) embedded MspA-M.

a Representative binding events of Cys, Hcy or GSH acquired with Au(III) embedded MspA-M nanopore. b The histogram of ΔI/I0 with corresponding Gaussian fittings from events of Cys, Hcy, and GSH. (N = 330 for each distribution). c The bar plot of the mean ΔI/I0 values of Cys, Hcy, and GSH. (Cys: 0.104 ± 0.0006, Hcy: 0.128 ± 0.004, GSH: 0.154 ± 0.011). All means and standard deviations were from three independent experiments for each analyte (10 min continuous recordings, Supplementary Tables 6, 8, 10).