Fig. 6: Prevention of a STm-induced mouse model of colitis with LCB.
a Experimental design for prevention. Mice were co-administrated with an equal amount (1 × 109 CFU) of STm and LCB. Equivalent doses of uncoated EcN and blank PBS were administrated as controls. Mice were sacrificed at day 6 post-administration. b The bacterial counts of STm in feces and cecum. c The ratios of EcN/STm in feces and cecum. d Levels of cytokines including IL-6 and IFN-γ in serum. e Mean MPO positive cells counted in cecum. f Typical images of MPO staining of cecum. Error bars represent standard deviation (n = 5). Significance was assessed using Student’s t-test, giving p values, *p < 0.05, **p < 0.01, ***p < 0.005. Scale bar: 50 μm.
