Table 3 Top exercise and inactivity-responsive genes in healthy individuals.

From: Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

 

Acute aerobic, logFC

Acute aerobic, FDR

Acute resistance, logFC

Acute resistance, FDR

Inactivity, logFC

Inactivity, FDR

Training aerobic, logFC

Training aerobic, FDR

Training resistance, logFC

Training resistance, FDR

NR4A3

2.99

2.0E − 07

2.95

8.2E − 15

 − 0.32

9.4E − 02

0.13

5.7E − 01

 − 0.03

8.7E − 01

EGR1

2.47

3.8E − 08

1.49

2.0E − 04

0.42

9.7E − 02

0.17

4.6E − 01

 − 0.04

8.8E − 01

FOS

2.20

5.7E − 06

1.41

1.5E − 04

0.09

8.5E − 01

0.07

8.9E − 01

 − 0.56

1.4E − 01

MAFF

2.03

3.0E − 05

2.60

1.7E − 12

0.15

4.6E − 01

0.14

2.1E − 01

0.14

3.7E − 01

CYR61

1.84

9.0E − 05

1.50

5.4E − 06

0.30

3.6E − 02

0.21

2.8E − 01

 − 0.25

4.0E − 01

GADD45G

 − 0.70

2.7E − 03

 − 1.25

2.3E − 08

0.08

7.3E − 01

 − 0.08

8.1E − 01

 − 0.14

3.6E − 01

CA4

 − 0.59

4.3E − 03

 − 0.23

2.3E − 03

0.06

5.9E − 01

0.03

9.2E − 01

0.02

8.6E − 01

MSTN

 − 0.42

6.3E − 03

 − 0.96

5.0E − 12

0.67

2.4E − 09

 − 0.32

1.4E − 01

 − 0.23

6.5E − 02

ADH1C

 − 0.39

2.4E − 05

 − 0.47

9.9E − 04

0.24

7.7E − 02

 − 0.26

9.3E − 02

 − 0.11

2.6E − 01

LGALSL

 − 0.39

2.7E − 04

 − 0.07

5.9E − 01

 − 0.23

7.1E − 03

0.02

9.1E − 01

0.00

1.0E+00

ANKRD1

0.94

2.3E − 02

2.81

1.0E − 11

0.41

3.8E − 01

0.13

7.7E − 01

0.14

6.2E − 01

ATF3

1.13

2.2E − 04

2.73

7.7E − 10

 − 0.13

4.9E − 01

0.18

2.8E − 01

0.09

5.1E − 01

TNFRSF12A

0.90

3.4E − 04

2.60

3.8E − 25

 − 0.21

4.5E − 01

0.23

2.0E − 01

 − 0.03

8.8E − 01

ARRDC2

 − 0.33

7.5E − 02

 − 1.18

8.2E − 13

0.63

1.1E − 11

 − 0.20

2.6E − 01

 − 0.13

1.7E − 01

LRRC66

 − 0.13

2.8E − 01

 − 1.10

3.0E − 07

0.15

3.8E − 02

 − 0.06

6.1E − 01

 − 0.16

2.8E − 02

CIART

 − 0.16

4.6E − 01

 − 1.00

4.0E − 15

 − 0.02

9.1E − 01

0.19

4.5E − 01

 − 0.13

2.5E − 01

DDIT4

0.10

8.2E − 01

 − 0.96

4.9E − 17

0.34

1.8E − 02

 − 0.22

4.2E − 01

 − 0.28

5.1E − 02

PFKFB3

0.41

1.2E − 01

 − 0.68

9.3E − 05

1.01

1.3E − 05

 − 0.29

4.3E − 01

 − 0.17

6.0E − 01

CHRNA1

0.15

4.5E − 01

 − 0.12

6.2E − 01

0.88

1.0E − 08

0.19

4.7E − 01

0.22

1.2E − 02

GADD45A

0.89

8.4E − 06

0.82

1.8E − 03

0.86

1.8E − 11

0.17

5.1E − 01

0.16

5.2E − 01

CHRND

0.13

3.6E − 01

0.00

9.9E − 01

0.85

4.8E − 05

 − 0.01

9.8E − 01

0.14

1.5E − 01

HSD52

    

0.73

8.4E − 04

  

 − 0.42

1.9E − 01

CA14

0.01

9.8E − 01

 − 0.17

3.8E − 01

 − 1.20

9.7E − 05

0.28

2.3E − 01

0.24

2.2E − 01

NMRK2

0.36

1.1E − 01

0.53

4.5E − 02

 − 1.19

5.4E − 06

0.54

1.6E − 01

0.83

1.8E − 05

SMCO1

 − 0.09

3.7E − 01

 − 0.15

1.1E − 01

 − 0.87

5.2E − 15

 − 0.15

2.1E − 01

 − 0.35

8.2E − 04

COLQ

0.16

3.1E − 01

0.74

5.0E − 06

 − 0.81

4.8E − 12

0.12

4.2E − 01

 − 0.15

9.3E − 02

EXTL1

 − 0.02

9.0E − 01

 − 0.15

5.2E − 02

 − 0.79

5.1E − 08

0.21

7.4E − 02

 − 0.10

1.9E − 01

CDK2

0.19

2.9E − 03

0.09

4.0E − 01

 − 0.06

3.9E − 01

0.40

1.4E − 05

0.21

3.5E − 05

ITGA6

0.06

6.0E − 01

 − 0.02

9.2E − 01

0.08

4.6E − 01

0.34

5.1E − 04

0.17

9.5E − 04

SCO1

0.04

5.9E − 01

 − 0.08

1.5E − 01

0.06

3.7E − 01

0.32

7.1E − 03

0.02

8.0E − 01

SRGN

0.45

3.8E − 08

0.05

6.4E − 01

 − 0.06

7.1E − 01

0.32

3.3E − 03

0.25

6.6E − 03

MYH9

0.61

1.6E − 03

0.62

2.0E − 08

 − 0.06

7.7E − 01

0.31

5.1E − 03

0.24

1.8E − 02

HIST1H1C

 − 0.20

2.4E − 01

0.00

1.0E+00

0.26

2.5E − 06

 − 0.40

2.6E − 03

 − 0.11

1.1E − 01

SH3RF2

 − 0.14

3.7E − 01

0.03

8.4E − 01

0.55

1.1E − 06

 − 0.34

7.3E − 03

 − 0.27

8.7E − 03

FHL3

0.01

9.5E − 01

 − 0.01

9.1E − 01

 − 0.02

9.4E − 01

 − 0.32

6.1E − 03

 − 0.06

7.0E − 01

SCN1B

0.08

3.2E − 01

 − 0.07

2.6E − 01

 − 0.01

9.3E − 01

 − 0.30

4.6E − 03

 − 0.19

9.2E − 03

DYRK2

 − 0.30

6.0E − 03

 − 0.11

6.5E − 01

0.04

8.3E − 01

 − 0.28

8.8E − 03

 − 0.09

7.8E − 02

MXRA5

0.11

6.7E − 01

 − 0.15

6.5E − 01

 − 0.27

3.3E − 01

0.63

2.9E − 01

1.20

8.5E − 06

COL3A1

0.17

4.6E − 01

0.10

7.2E − 01

 − 0.05

9.4E − 01

0.51

2.0E − 01

1.01

1.7E − 11

COL4A1

0.38

1.3E − 02

0.24

3.3E − 01

 − 0.10

5.3E − 01

0.63

5.9E − 02

0.86

1.3E − 09

COL1A2

0.17

3.4E − 01

0.08

7.4E − 01

0.12

7.7E − 01

0.38

2.2E − 01

0.86

2.5E − 07

MYH1

 − 0.07

8.2E − 01

 − 0.32

1.3E − 01

0.70

1.8E − 03

 − 0.84

1.6E − 01

 − 0.92

8.3E − 04

CALML6

 − 0.29

2.5E − 01

 − 0.06

8.3E − 01

0.23

3.7E − 01

 − 0.59

1.5E − 01

 − 0.75

1.3E − 05

METTL21C

 − 0.01

9.5E − 01

 − 0.30

3.4E − 01

0.11

6.8E − 01

 − 0.17

1.2E − 01

 − 0.60

7.9E − 03

MYLK2

 − 0.12

3.0E − 01

 − 0.23

9.7E − 03

0.09

6.6E − 01

 − 0.35

4.5E − 02

 − 0.45

2.9E − 06

PAIP2B

 − 0.15

9.1E − 02

 − 0.16

1.5E − 01

 − 0.34

4.2E − 03

 − 0.01

9.8E − 01

 − 0.40

2.2E − 04

  1. Table presents the log(fold-change) before-after intervention and the false discovery rate (FDR)