Fig. 2: U1 over-expression decreases cell migration and invasion of HeLa cells in vitro.

HeLa cells were transfected with control empty vector or U1 expression plasmids. a Cell growth determined in 24 h intervals. The data are represented as mean ± SD (n = 3, independent cell culture). b, c Cell migration and invasion were measured 24 h after transfection. The bars indicate mean ± SD (n = 3, independent cell culture). P-value was calculated with two-tailed Student’s t-test. d, e Cell migration and invasion were determined 24 h post-transfection and imaged by phase-contrast microscopy (10x magnification). Scale bar = 250 µm. Source data are provided as a Source Data file.