Fig. 4: The TMZ sensitivity enhanced by BIP-MPC-NP in LN229R cells. | Nature Communications

Fig. 4: The TMZ sensitivity enhanced by BIP-MPC-NP in LN229R cells.

From: Dual functionalized brain-targeting nanoinhibitors restrain temozolomide-resistant glioma via attenuating EGFR and MET signaling pathways

Fig. 4

a, b The EdU assay and colony formation assay of LN229R with treatments of TMZ and different nanoinhibitors. The histogram displayed the statistics of EdU assay and colony formation assay, respectively (n = 3). Scale bar = 50 μm. c, d The cell apoptosis assay and the cell-cycle analysis were performed with flow cytometry in LN229R. The histogram displayed the statistics of apoptosis assay and the cell-cycle analysis, respectively (n = 3). The error bars represent the S.D. of three measurements. P value was determined by Student’s t-test. Significant results are presented as *P < 0.05, **P < 0.01, ***P < 0.001.

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