Fig. 7: Role of CD11c+ DCs in antitumor effects of tumor cell vaccination.
From: Vaccination with CD47 deficient tumor cells elicits an antitumor immune response in mice
a Schematic outline of the experimental design. b Flow cytometry profiles showing deletion of CD11c+ DCs in DT-injected mice (analysed 1 day after the last DT injection). c Tumor growth in CD11c-DTR→B6 BM chimeras that were vaccinated with media, or with irradiated CD47KO B16F0 with or without DT treatment (n = 5 per group), followed 7 days later by subcutaneous injection of 2 × 105 WT B16F0 melanoma cells. Tumor growth is shown as tumor volumes (mean ± SEM) over time. Source data are provided as a Source Data file.
