Table 2 Associations between clinical variables and [11C]UCB-J VT.

From: Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

 

PANSS total correlation coefficient

p Value

PANSS-positive correlation coefficient

p Value

PANSS-negative correlation coefficient

p Value

PANSS general correlation coefficient

p Value

Chlorpromazine-equivalent dose correlation coefficient

p Value

Duration of illness correlation coefficient

p Value

Hippocampus

−0.09

0.71

−0.11

0.69

−0.10

0.72

−0.04

0.89

−0.36

0.14

−0.15

0.56

Frontal cortex

−0.13

0.61

−0.07

0.80

−0.09

0.73

−0.14

0.60

−0.34

0.17

−0.29

0.24

Anterior cingulate cortex

−0.04

0.87

0.02

0.93

−0.09

0.73

−0.04

0.89

−0.32

0.20

−0.33

0.17

  1. Associations between PANSS scores (total and positive, negative and general subscale scores), chlorpromazine-equivalent dose and duration of illness and [11C]UCB-J VT were explored in the schizophrenia group (n = 18) in the hippocampus, frontal cortex and anterior cingulate cortex. There were no significant associations between PANSS scores, chlorpromazine-equivalent dose or duration of illness and [11C]UCB-J VT in any of the regions of interest. All correlation coefficients reported are Pearson product–moment correlation coefficients, except where use of italics signifies Spearman’s rank correlation coefficients for nonparametric data
Back to article page