Fig. 2: Scatter plot of genetic associations.
From: A robust and efficient method for Mendelian randomization with hundreds of genetic variants
Genetic associations with HDL-cholesterol (standard deviation units) against genetic associations with CHD risk (log odds ratios). These association estimates are the inputs for the contamination mixture method. Error bars for genetic associations are 95% confidence intervals. Heavy black line is the causal estimate from the contamination mixture method with the strongest signal, lighter black line is the causal estimate from the secondary peak. The grey area is the 95% confidence interval for the causal effect; this comprises two ranges as the likelihood is bimodal.
