Fig. 2: Milk secretion is impaired in Tardbp−/− female mice.
From: TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh
a Analysis of milk volume from mammary glands of wild-type (WT) and Tardbp−/− female mice following 10 U of oxytocin stimulation (n = 7 for each genotype). b Analysis of triacylglycerols (TAGs) in milk collected from WT and Tardbp−/− mice at lactation day 2 (L2) (n = 6 for each genotype). c, d Analysis of TAGs in mammary gland epithelial cells (MECs) collected from WT and Tardbp−/− mice at L2 (C) (n = 5 for each genotype) or L10 (D) (n = 6 for each genotype). Data are means ± SD (a) or means (b–d). TAG levels in MECs were normalized to protein concentration of each sample. Unpaired t test was used to evaluate statistical significance. *P < 0.05, ***P < 0.001. Source data are provided as a Source Data file.
