Table 1 Positive selection on mammalian TARDBP and SRSF9.

From: TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh

Gene

lnL0

lnL1

2ΔlnL

dN/dS

Positive selection site

TARDBP

−5443.244

−5437.227

12.04*

371.37

352P*, 360Q

SRSF9

−1846.979

−1852.675

11.39*

12.41

1N, 22V, 44R, 129R, 159R

  1. lnL log likelihood, lnL0 LnL under model A null hypothesis, lnL1 LnL under model A alternative hypothesis
  2. *Five percent significance level