Fig. 2: Impact of nctA deletion upon A. fumigatus growth. | Nature Communications

Fig. 2: Impact of nctA deletion upon A. fumigatus growth.

From: The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

Fig. 2

a Colonial growth phenotypes of the wild-type MFIG001 (WT), the nctA null (∆nctA) and the nctA reconstituted strain (nctA rec) grown on a solid Aspergillus complete medium (ACM) for 72 h at 37 °C. b Radial growth phenotypes on solid ACM, Aspergillus minimal medium (AMM), RPMI-1640 and DMEM. The error bars represent standard error of the mean of three independent experiments. c Germination rates in liquid RPMI-1640 at 37 °C. P-value was calculated by repeated measures two-way ANOVA with Sidaks correction: ****P < 0.0001; NS, P > 0.05. The error bars signify the standard deviations. d Hyphal extension rates in RPMI-1640 at 37 °C. P-value was calculated by Kruskal–Wallis test with Dunn’s correction: ****P < 0.0001; NS, P > 0.05. Percentages of germination rates and hyphal extension rates were measured under the microscope. The error bars represent standard error of the mean. Source data are provided as a Source Data file.

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