Fig. 4: Genome-wide binding profile of NctA.
From: The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus
a Venn diagram showing the overlap of NctA-binding peaks (q-value < 0.01, fold enrichment >1.5) obtained from no-drug and the 0.5 mg/L itraconazole-treated conditions. b Distribution of the ChIP-seq peak location with respect to annotated genes. The frequency distribution of the distance between the merged peak summit of the significant binding peak regions (q-value < 0.01, fold enrichment >1.5) and the translation start site (ATG) of the nearest annotated gene is plotted. c Conserved nucleotide motifs identified in the NctA ChIP-seq peak regions. A summary of the de novo motif discovery analysis is shown with the identified consensus motifs and its sequence logos, the calculated e-values, and the frequency of the appearance of the motifs within the ChIP-seq peak set are analysed. Source data are provided as a Source Data file.
