Fig. 6: Deconstruction of DWS/DCS with iNIRS. | Nature Communications

Fig. 6: Deconstruction of DWS/DCS with iNIRS.

From: Time-of-flight resolved light field fluctuations reveal deep human tissue physiology

Fig. 6

a in vivo iNIRS TOF-resolved field autocorrelations, or individual components thereof, can be integrated in TOF to generate DWS/DCS-like autocorrelations. For TOF-integrated DWS/DCS-like autocorrelations, \({{G}}_1^{{\mathrm{DCS}}}\), fitting the entire autocorrelation with DWS/DCS theory results in a poor fit (b). Fitting early time lags, where the cumulant approximation is valid, results in a considerably higher adjusted R2 value, but the fit diverges from the data at large time lags (c). On the other hand, integrating just the iNIRS fast component (red) or the iNIRS early time lag single exponential fit (cyan), yields autocorrelations in better agreement with DWS/DCS theory across time lags and adjusted R2 approaches 1 regardless of fit region (b–c).

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