Fig. 3: Trajectory analysis of uveal melanoma cells.
From: Single-cell analysis reveals new evolutionary complexity in uveal melanoma
a Enriched transcription factor motifs determined using SCENIC analysis of 8,598 tumor cells and displayed as a heatmap of z-scored enrichment values. b Monocle 2 trajectory analysis of 7,947 uveal melanoma cells obtained by 5′ gene expression chemistry annotated by calculated states. c Trajectory analysis annotated by sample and overlaid with color by GEP class. d Combined Monocle 2 trajectory analysis displayed by each sample and annotated by calculated state. e Chart depicting pathways found to be significant by MSigDB analysis of each sample cluster determined by BEAM analysis followed by hierarchical clustering.
