Fig. 6: Control experiments. | Nature Communications

Fig. 6: Control experiments.

From: Functionalization of remote C(sp3)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes

Fig. 6

[a] 2o (0.1 mmol), 3a (0.2 mmol, 2.0 equiv), (CuOTf)2·C6H6 (0.05 equiv), tBu3-TERPY (0.1 equiv), K2CO3 (2.0 equiv), DCE (2.0 mL, c 0.05 M), 45 °C, under nitrogen atmosphere. [b] 1t (0.2 mmol), 3t (0.4 mmol), CuI (0.1 equiv), tBu3-TERPY (0.2 equiv), K2CO3 (2.0 equiv), CH3CN (1.0 mL, c 0.2 M), 60 °C, under nitrogen atmosphere.

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