Fig. 6: Detection of H2S in blood samples. | Nature Communications

Fig. 6: Detection of H2S in blood samples.

From: H2S-activatable near-infrared afterglow luminescent probes for sensitive molecular imaging in vivo

Fig. 6

a Afterglow images of F12+-ANP in blood samples freshly collected from 10 healthy persons, 10 HCC patients, and 10 CRC patients. Freshly collected bloods were 2-fold diluted with PBS buffer (1×, pH 7.4), and then incubated with F12+-ANP (58/28/2.2 μg mL−1 F12+(BF4)2/MEH-PPV/NIR775) at 37 °C for 1 min, followed by irradiation with the 808-nm laser (1 W cm−2) for 1 min. After removal of the laser, the afterglow luminescence images were immediately acquired for 60 s with an 790 nm filter. b Afterglow luminescence intensities of F12+-ANP in 2-fold diluted blood samples. c Quantification of H2S concentrations in whole blood of healthy persons and HCC or CRC patients. Data denote mean ± s.d. (***P < 0.001, n = 10). Statistical differences were analyzed by Student’s t test. Source data are provided as a Source Data file.

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