Fig. 4: Additive effects of the interventions on the 1-month airway samples.

Relative abundances are shown on (a) Phylum level and (b) Genus level. The correlation was analyzed by Spearman’s rank correlation coefficient and p-values below 0.05 are shown. The p-values in b are not significant when correcting for multiple testing using an FDR corrected significance of 0.1. Boxplots with first and third quartiles corresponding to the lower and upper hinge, the median represented by a vertical line, the mean by a black dot, upper/lower whiskers extend to the largest/smallest value no further than 1.5 * inter-quartile range (IQR) from the hinge, and outliers are shown as gray circles. n = 144, 266, and 131 for the zero, one, and two intervention groups, respectively. Source data are provided as a Source Data file.