Fig. 5: Associations between intervention driven microbiota changes in the 1-month airway and neonatal airway immunology.

PCo1 from Fig. 3 was used as a metric for the intervention driven microbial changes and analyzed with the airway concentration of 20 local immune mediators in the nose, also measured at the 1-month time point. Linear models show that PCo1 is associated with several immune mediators, expressed as relative concentration ratios of immune mediators per standard deviation (SD) increase in PCo1, n = 585 independent samples. Error bars represent 95% confidence intervals. Source data are provided as a Source Data file.