Fig. 2: Results on non-parametric simulations.
From: Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig

a Median activity difference between the reconstructed trajectories and the ground truth. Lines correspond to the simulations with 0, 1, 2, or 3 changepoints. The median in computed across all signatures and time points in the sample. b Distribution of maximum activity change (MAC) discrepancies between between estimated activities and ground truth.