Fig. 2: Mendelian randomisation analysis for individual SNPs associated with accelerometer-measured physical activity in relation to colorectal cancer risk (overall, colon, rectal) using the genetic instrument from the GWAS by Doherty et al.11.
From: Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis
The x axis corresponds to a log OR per one unit increase in the physical activity based on the average acceleration (milli-gravities). The Mendelian randomisation (MR) result corresponds to a random effects model due to heterogeneity across the genetic instruments. logOR = log odds ratio (black filled circle). 95% CI = 95% confidence interval (black line). SNP single nucleotide polymorphism.
