Fig. 2: The spatial organization of dendritic excitatory inputs on individual V1 neurons.
From: Spatiotemporal functional organization of excitatory synaptic inputs onto macaque V1 neurons
a Two-photon image of an example neuron (depth of 127 μm on Day 71 post-injection) expressing SF-iGluSnFR.A184S in V1 superficial layers. The image was averaged across 1000 frames. Scale bar, 20 µm. b Map of orientation-selective ROIs on dendrites of the example neuron. Orientation preferences are colored for vector sum polarity for each ROI (refer to colorbar at the lower right). c Map of SF preferences of the orientation-selective inputs. SF preferences are colored for fitting maximum for each ROI. d Map of color-selective inputs. Color preferences are labeled with the dominant polarity for each ROI. e A functional preference map of dendritic inputs. ROIs are colored for the orientation vs. color index. f Relationship between the dendritic distance of ROI pairs (18,581 ROI pairs in total from 23 neurons) and their tuning correlation coefficients (top left, orientation tuning correlation among orientation-selective ROIs; top right, SF tuning correlation among orientation-selective ROIs; bottom left, color tuning correlation among color-selective ROIs; bottom right, RF correlation among orientation-selective ROIs). Data points are fitted with an exponential curve (red), and shuffled data are presented as a reference (gray dashed). Error bar, SEM.
