Table 1 Synthesis of [2]rotaxanes from 24-crown-8, amine 5 and C=O/C=S/SO2/P=O electrophiles 7–14a

From: Weak functional group interactions revealed through metal-free active template rotaxane synthesis

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  1. aReaction conditions: 1 equiv. each of crown ether 1, amine 5 and electrophile 7–14, toluene [0.14 M], rt.
  2. bYield of isolated product.
  3. c1.5 equiv. of electrophile.
  4. d2 equiv. of Et3N added.
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