Fig. 1: Manhattan plot of the combined meta-analysis of GWAS of SCC. | Nature Communications

Fig. 1: Manhattan plot of the combined meta-analysis of GWAS of SCC.

From: Genome-wide meta-analysis identifies eight new susceptibility loci for cutaneous squamous cell carcinoma

Fig. 1

The Pfixed Stage one value for all SNPs present in at least two studies have been plotted using a −log10(p-value). The total Stage one meta-analysis included eight SCC GWAS, totaling 19,149 cases and 680,049 controls. p < 5 × 10–8 (genome-wide significance) threshold is indicated by a dashed line. In total, 22 loci reached genome-wide significance, including 8 novel loci 1q21.3, 2q33.1, 6q15, 8q23.3, 9p23, 11p15.4, 12q13.3, and 12q23.1 are highlighted by *.

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