Fig. 2: Antibody IgG affinity and avidity measured by SPR after HIV-1 Env vaccination.
From: Immune checkpoint modulation enhances HIV-1 antibody induction
a, b Purified plasma IgG (a) binding and (b) avidity as measured by surface plasmon resonance (SPR) to CH505 TF gp120 and CH505 TF SOSIP trimer proteins. Each dot represents a single animal and are colored based on the antibody treatment group (CTLA-4, blue; PD-1, red; CTLA-4 + PD-1, green; Control CH65, purple). c, d Purified plasma IgG (c) binding and (d) avidity as measured by surface plasmon resonance (SPR) to CH848 DT and CH848 WT SOSIP trimer proteins. Each dot represents a single animal and are colored based on the antibody treatment group (CTLA-4, blue; Control CH65, purple). Source data are provided as a Source Data file.
