Fig. 1: Developmental effects.
From: Maturation of the human striatal dopamine system revealed by PET and quantitative MRI
Age related-differences in Raclopride assessment of available D2/D3 receptor concentration (N = 78 individuals, 128 sessions; outlier removals: NAcc = 3, putamen = 1, caudate = 1), DTBZ assessment of VMAT2 concentration (N = 74 individuals, 119 sessions; outlier removals: NAcc = 1, putamen = 2, caudate = 0), and R2′ assessment of tissue iron content (N = 121 individuals, 180 sessions; outlier removals: NAcc = 2, putamen = 1, caudate = 2) in the striatum. All analyses were conducted using linear mixed-effects models. Model parameters can be found in Table 1.+p < 0.05 uncorrected, *p < 0.05, ***p < 0.001, ****p < 0.0001 Bonferroni corrected. DTBZ BP [11C]Dihydrotetrabenazine binding potential; Raclopride BP [11C]Raclopride binding potential.
