Fig. 3: The Fd-binding pocket of NDH-1L.
From: Structural insights into NDH-1 mediated cyclic electron transfer
a Two orthogonal views of the peripheral arm of NDH-1L in complex with Fd. Proteins are colored as in Fig. 1b and ion-sulfur clusters are shown as spheres. b Electrostatic surface potential of the Fd-binding pocket at the peripheral arm of the NDH-1L complex (positive potential, blue; negative potential, red). Fd is presented in cartoon model and colored in teal. c Close-up views of key Fd-interacting residues of NdhI, NdhH, NdhV, and NdhO. d The Fd-binding pocket of NDH-1L highly resembles that of PSI (left). Fd binds to NdhI in a similar manner as Fd to PsaC (middle). The distance and angular relationships between the [2Fe-2S] cluster in Fd and [4Fe-4S] clusters in NDH-1L and PSI (right). Arrows indicate the direction of electron flow. e The overall electrostatic surface potential of the Fd-binding pockets is highly positive in NDH-1L and close to neutral in PSI.
