Table 3 Echocardiographic parameters in the mice with established cardiac dysfunction treated with B38-CAP for 2 weeks.

N

5

5

6

6

6

6

Age (weeks)

15

17

15

17

15

17

BW (g)

23.14 ± 1.24

25.82 ± 1.03

23.12 ± 0.87

25.92 ± 0.74

23.55 ±± 0.83

24.30 ± 1.16

HR (bpm)

594 ± 49

631 ± 68

551 ± 51

559 ± 49

570 ± 65

644 ± 61

FS (%)

51.78 ± 4.09

51.91 ± 1.56

29.49 ± 2.79***

27.20 ± 1.43

29.06 ± 2.36***

36.38 ± 2.03^{### ††}

EF (%)

76.70 ± 3.70

83.89 ± 1.27

57.44 ± 4.5***

53.56 ± 2.28

56.70 ± 3.54***

67.03 ± 2.86^{### ††}

LVESD (mm)

1.54 ± 0.15

1.54 ± 0.13

2.43 ± 0.38***

2.75 ± 0.14

2.49 ± 0.23***

2.15 ± 0.17^{## †}

LVEDD (mm)

3.20 ± 0.08

3.21 ± 0.22

3.44 ± 0.45

3.77 ± 0.17

3.51 ± 0.34

3.38 ± 0.24

IVSD (mm)

0.74 ± 0.04

0.79 ± 0.03

1.05 ± 0.17*

1.04 ± 0.05

1.09 ± 0.05***

0.99 ± 0.07^†

PWD (mm)

0.78 ± 0.06

0.89 ± 0.13

1.11 ± 0.12***

0.99 ± 0.05

1.03 ± 0.06***

1.08 ± 0.09