Fig. 1: Schematic of the experimental apparatus for the online proteolysis by microdroplet chemistry coupled with mass spectrometry (ESSI-MS).
From: Ultrafast enzymatic digestion of proteins by microdroplet mass spectrometry

The inner capillary has an i.d. of 50 µm and an o.d. of 148 µm to which a high voltage (typically +3 kV or −3 kV) is applied.