Fig. 7: Non-coding source gene expression from lung cancer patient samples in healthy tissues. | Nature Communications

Fig. 7: Non-coding source gene expression from lung cancer patient samples in healthy tissues.

From: Integrated proteogenomic deep sequencing and analytics accurately identify non-canonical peptides in tumor immunopeptidomes

Fig. 7

A comparison of presumed non-coding source gene expression in the investigated samples to that in healthy tissues (GTEx). a Heatmap of lncRNA source genes showing the 90th percentile gene expression levels across 30 healthy tissues on the left and the gene expression levels identified in lung tissue samples on the right. Tissue gene expression was classified as not expressed (90th percentile TPM ≤ 1) in any, 1–3, or >3 tissues other than testis to assess tumor specificity. The number of HLAIp identified per gene is depicted as well as the gene (GENCODE) and sample type. b Specifically, this was also plotted for the tumor-specific noncHLAIp identified in lung cancer patient C3N-02289. Source data are provided as a Source Data file.

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