Fig. 4: Ligand binding and signaling assays of the wild-type (WT) FPR2 and mutants.
From: Structural basis of ligand binding modes at the human formyl peptide receptor 2
Dose–response curves were generated from at least three independent experiments performed in triplicate. Data are shown as mean ± s.e.m. Source data are provided as a Source Data file. a–d Saturation binding of WK(FITC)YMVm. See Supplementary Table 1 for detailed statistical evaluation. e–h WKYMVm-induced IP accumulation assay using a chimeric Gα protein GαΔ6qi4myr. See Supplementary Table 2 for detailed statistical evaluation. i Binding of WK(FITC)YMVm inhibited by fMLFK. See Supplementary Table 1 for detailed statistical evaluation. j fMLFK-induced IP accumulation assay. See Supplementary Table 2 for detailed statistical evaluation.
